The Arrow of Poison (II) applies the Poison II effect upon hitting a target. This effect inflicts poison damage at a faster rate than the standard Poison effect, quickly draining the target's health over a shorter period. However, Poison cannot reduce a target's health below half a heart, meaning it will not deliver a fatal blow.

This Arrow of Poison (II) can be obtained either by crafting or by using a cauldron. To craft it, players must surround 8 arrows with a Lingering Potion of Poison (II) in a crafting table. Alternatively, it can be made by dipping arrows into a cauldron filled with a Potion of Poison (II).

The Infinity enchantment does not apply to this Arrow of Poison (II), meaning each shot consumes an arrow from the player's inventory.