Slimeballs are a crafting ingredient commonly dropped by slimes and can also be sneezed out by pandas. Baby pandas have a 1⁄700 chance of dropping a Slimeball when sneezing. Wandering traders sometimes offer to sell a Slimeball for 4 emeralds.

Slimeballs are primarily used to craft leads, magma cream, slime blocks, and sticky pistons. They can also be used to breed frogs and reduce the remaining growth duration of tadpoles by 10%. Both frogs and tadpoles follow a player holding a Slimeball.